PRODOMAIN.INFO - Prodomain

1. Prodomain definition and meaning | Collins English …

collinsdictionary.com - Prodomain definition: Collins Dictionary Definition | Meaning, pronunciation, translations and examples

2. ProDemand Automotive Repair Information - Mitchell1, …

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4. Re: What is the function of a protein's prodomain? Why …

madsci.org - May 18, 2006  · In this case the term "prodomain" is used, because the N-terminal region is folded into a discrete structural unit with a specific function (the definition of a domain). Usually the prodomain mediates interaction with other proteins in a complex. Proteolytic cleavage then removes the prodomain, activates the caspase and triggers a cascade in ...

5. Prodomain mutations at the subtilisin interface: …

nih.gov - Nov 28, 1995  · In the complex, the prodomain packs against the two parallel surface helices of subtilisin (residues 104-116 and residues 133-144) and supplies caps to the N-termini of the two helices. The binding site is contained almost entirely in the linear sequence 100-144 of subtilisin. The C-terminus of the prodomain (residues 72-77) extends out from ...

6. The prodomain of caspase-3 regulates its own removal …

nature.com - Jan 28, 2019  · The 28 amino acid prodomain of caspase-3 is highly conserved (Fig. S1A), therefore we sought to determine if there were specific regions within the prodomain that were important for its function ...

7. Recombinant human BDNF proDomain protein | Alomone Labs

alomone.com - Recombinant human brain-derived neurotrophic factor prodomain protein (#B-245) from Alomone Labs is produced in E. coli. 100% net peptide content. Sterile & endotoxin free. Free samples available. Lyophilized. Global shipping at room temperature. Your top supplier for growth factors.

8. Prodomain–growth factor swapping in the structure of pro-TGF-β1

sciencedirect.com - Feb 02, 2018  · Prodomain–GF interfaces are important not only for latency but also for biosynthesis. The prodomain is required for proper folding and dimerization of the GF domain ( 10, 11 ). The C-terminal GF domain folds either concomitantly with or subsequently to the N-terminal prodomain ( 10, 12, 13 ). The structure of the pro-TGF-β1 dimer reveals ...

9. Anti-Caspase 12 Antibody, prodomain, aa 100-116 | AB3612

emdmillipore.com - Caspase-12 is predicted to have a large, >120 aa, long prodomain region. Thus this antibody recognizes only the proforms of the enzyme and not the active subunits. Uncleaved (proform) caspase-12 is prominently detected in many tissues. Active forms are difficult to detect expect in transfect cell systems. {Kalai, M et al (2003) 162:457-467}.

10. INDUCTION MECHANISM OF CELL DEATH AND PATHOGEN …

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11. Growth factors and hormones pro‐peptides: the unexpected …

wiley.com - Feb 20, 2017  · In this review, we discuss the various classical functions of prodomains, and the biological consequences of these pro‐peptides acting as ligands. We will focus our attention on the brain‐derived neurotrophic factor prodomain (pBDNF), which has been recently described as a novel secreted ligand influencing neuronal morphology and physiology.